The effect of Leptadanea hastata stem on some cultured microorganisms

Authors

  • H. Ibrahim Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria Author
  • J. O. Amupitan Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria Author
  • P. H. Coombes Natural Products Research Group, School of Pure and Applied Chemistry, University of Kwazulu Natal, Durban 4041, South Africa. Author

Keywords:

Leptadanea hastata, microorganisms, Ethnomedicine

Abstract

An ethanol extract of the stem of Leptadanea hastata (Pers) Decne was partitioned between chloroform and water. Saponins were detected in the aqueous fraction, while the chloroform fraction, which showed significantly inhibitory activity against E. coli, Klebsiella pneumonae, Staphylococcus aureus, Pseudomonas sp. and Salmonella sp. bacteria, was shown to contain alkaloids. The chloroform fraction was further partitioned into aqueous methanol and petroleum ether. The aqueous methanol portion showed activity against only K. pneumonae while the pet. ether portion showed activity against E. coli,
 Pseudomonas sp. and salmonella sp. These results justify the use of the plant in ethnomedicine.

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Published

2025-02-25

Issue

Vol. 2 No. 1 (2005): ChemClass Journal

Section

Articles