The anti-venom potential of the stem bark of Boswellia dalzielli on saw-scaled viper venom

Authors

  • E. L. Genwa Chemistry Department, Boys’ Secondary School P.M.B. 01001, Gindiri, Plateau State Author
  • H. Yero Dept of Chemistry, College of Education, Gindiri, Plateau State. Author

Keywords:

Boswellia dalzielli, anti-venom, stembark

Abstract

Boswellia dalzielli known as ‘Ararabi’ in Hausa belongs to the family Burceraceae. It is an aromatic tree
 with a height of up to 13 m and has a pale brown bark. It is widespread in tropical Africa in savanna
 woodland, often near inselbergs and rocky areas. Saw-scaled viper (Echis carinatus) is 40 - 60 cm long
 and is a widely distributed species of snake especially in Africa and Asia. Its venom is hematoxic i.e. the
 venom is injurious to blood vessels. Studies on the methanol, acetone, chloroform and water extracts of
 the stem bark obtained by the cold extraction method revealed that the methanol extract ED50 of 0.58 ml
 has the highest efficacy. This was determined by injecting a group of rats with a viper venom of LD50 whose LD50 was predetermined to be 0.076 mg. The study shows that Boswellia dalzielli stem bark could be used for viper antivenom.

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Published

2025-03-01