Cytotoxic correlation of some traditional medicinal plants using brine shrimp lethality test

Abstract

Ten Nigerian traditional medicinal plants, C. nigricans Vahl.; P. biglobosa Benth.; C. alata Linn;
 J. curcas, C. paradisi Macf., S. angustifolia,  A. cordifolia Schum and Thonn.,  N. latifolia SM., E.
 senegalensis DC and V. album Linn belonging to a variety of plant families were extracted with various
 solvents.  The extracts were screened using the brine shrimp lethality bioassay to determine candidate
 plants for isolation of cytotoxic principles.  The calculated LC50 of the extracts ranged from
 11-500g/ml, except for C. paradisi and S. angustifolia with values > 1000g/ml, indicating the
 presence of cytotoxic compounds which could be potent against various human diseases